Fluconazole - Antifungal- Vaginal Candidiasis - 20 Tablets
Contain same as Diflucan 150mg.
Fluconazole is an antifungal medication used for a number of fungal infections.
This
includes candidiasis, blastomycosis, coccidiodomycosis, cryptococcosis,
histoplasmosis, dermatophytosis, and pityriasis versicolor.
It is
also used to prevent candidiasis in those who are at high risk such as
following organ transplantation, low birth weight babies, and those with
low blood neutrophil counts.
It is given either by mouth or by injection into a vein.
Fluconazole works by interfering with the formation of ergosterol. Ergosterol is an important component of the fungal cell wall. By inhibiting this component, fungal cells will die. Fluconazole can also inhibit the growth of new fungi.
In addition to treating candidiasis, fluconazole can also be used to treat meningitis caused by the Cryptococcus fungus (cryptococcal meningitis) and prevent fungal infections in people with weak immune systems, such as people with HIV/AIDS or chemotherapy recipients.
Fluconazole Dosage and Rules for Use
The dose of fluconazole prescribed by the doctor can vary for each patient. The following is the general dosage for fluconazole based on the purpose of use:
Purpose: Treating vaginal candidiasis and penile candidiasis (candidal balanitis)
Adults: 150 mg as a single dose.
Purpose: Treating recurrent vaginal candidiasis (≥4 times a year)
Adults: 150 mg, once every 3 days for a total of 3 doses (days 1, 4, and 7). Followed by a maintenance dose of 150 mg, once a week for 6 months.
Purpose: Treating oropharyngeal candidiasis
Adults: Initial dose of 200–400 mg on the first day, followed by 100–200 mg, once daily, for 7–21 days.
Children aged 0–14 days: Initial dose of 6 mg/kgBW, followed by 3 mg/kgBW every 72 hours. Maximum dose of 12 mg/kgBW every 72 hours.
Children aged 15–27 days: Initial dose of 6 mg/kgBW, followed by 3 mg/kgBW every 48 hours. Maximum dose of 12 mg/kgBW every 48 hours.
Children aged 28 days–11 years: Initial dose of 6 mg/kgBW, followed by 3 mg/kgBW, once daily.
Purpose: Prevent recurrence of oropharyngeal candidiasis in HIV patients
Adults: 100–200 mg, once daily, or 200 mg, 3 times weekly
Purpose: Treat esophageal candidiasis
Adults: Initial dose of 200–400 mg on the first day, followed by 100–200 mg, once daily for 14–30 days.
Children aged 0–14 days: Initial dose of 6 mg/kgBW, followed by 3 mg/kgBW, every 72 hours. Maximum dose of 12 mg/kgBW every 72 hours.
Children aged 15–27 days: Initial dose of 6 mg/kgBW, followed by 3 mg/kgBW, every 48 hours. Maximum dose of 12 mg/kgBW every 48 hours.
Children aged 28 days–11 years: Initial dose of 6 mg/kgBW, followed by 3 mg/kgBW, once daily.
Purpose: Prevent recurrence of esophageal candidiasis in HIV patients
Adults: 100–200 mg, once daily, or 200 mg, 3 times weekly.
Purpose: Treat invasive candidiasis
Adults: Initial dose of 800 mg on day 1, followed by 400 mg, once daily, for 2 weeks.
Children aged ≥4 weeks to 11 years: 6–12 mg/kgBW, once daily.
Purpose: Treat cryptococcal meningitis
Adults: Initial dose of 400 mg on day 1, followed by 200–400 mg, once daily, for 6–8 weeks. Continued with 200 mg, once daily, for up to 1 year from the start of initial treatment, for those at risk of recurrence.
Children aged ≥4 weeks to 11 years: 6–12 mg/kgBW, once daily. Maintenance dose 6 mg/kgBW, once daily.
Purpose: Chronic candidiasis in dentures
Adults: 50 mg, once daily, for 14 days.
Purpose: Treat candiduria (candida found in urine)
Adults: 200–400 mg, once daily, for 7–21 days.
Purpose: Treat chronic candidiasis of the skin
Adults: 50–100 mg, once daily, for 28 days.
Purpose: Prevent fungal infections in patients with impaired immune systems
Adults: 200–400 mg, once daily.
Children aged ≥4 weeks–11 years: 3–12 mg/kgBW, once daily.
Purpose: Tinea pedis, tinea corporis, tinea cruris
Adults: 150 mg, once a week, or 50 mg, once a day.
Purpose: Treating tinea versicolor
Adults: 300–400 mg, once a week, for 1–3 weeks, or 50 mg, once a day, for 2–4 weeks.
Purpose: Treating fungal nail infections (tinea unguium)
Adults: 150 mg, once a week.
The duration of treatment with fluconazole can vary from patient to patient, depending on the patient's immune condition. If the patient's immune condition is weak, fluconazole will be given longer.
