PHARMACOLOGY
Adapalene is a chemically stable compound with pharmacological activity similar to retinoids. Biochemical and pharmacological profile studies show that Adapalene is a potent modulator of cellular differentiation, keratinization and inflammatory processes where these processes represent important features in the pathology of acne vulgaris. Mechanistically, Adapalene binds to specific Retinoic acid nuclear receptors, but does not bind to cytosolic receptor proteins. Although Adapalene's exact mechanism of action is unknown. Topical adapalene is indicated to normalize follicular epital cell differentiation, thereby reducing microcomedoma formation.
How to Use:
- Apply Pharmalene to form a thin layer on areas of the face and/or body that have acne once a day after cleaning with a gentle cleanser. Use a pea-sized amount for each area of the face (e.g., forehead, cheeks, and chin). Avoid the eyes, lips and mucous membranes. Pharmalene is not for swallowing, eye use or intravaginal use
- Use within 60 days after opening
Benefits:
- Pharmalene B is indicated for topical therapy of acne vulgaris in patients aged 12 years and over
Contraindications:
Patients who have a history of hypersensitivity to Adapalane, Benzoyl Peroxide, or other components contained in the preparation
Attention :
- Should not be used on parts of the skin that are injured, cut, abrasion,
Side effects :
- Skin dries out
- Local rash on the skin
- Feeling burned out
- Irritation to the skin
- Redness
- More details are listed in the brochure in the packaging
Composition :
- Each gram of gel contains 1 mg adapalene
Storage Method: Store in a cool place
Packaging: Tube 10 Gr
